If we are to trace the golden thread of South and Central American shamanism—a thread that weaves through the bloody, miraculous surgeries of Pachita , the scientific investigations of Jacobo Grinberg , and the Toltec cosmology popularized by Carlos Castaneda—we inevitably arrive at a small, smoke-filled hut in the remote cloud forests of Oaxaca, Mexico. There, sitting on a dirt floor, illuminated only by the flickering light of beeswax candles and the glowing embers of copal incense, sits a frail, impoverished indigenous woman. She cannot read or write, she speaks no Spanish, and she has never heard of quantum physics or the Syntergic Lattice. Yet, through her profound mastery of the ancient, sacred fungi known as the Niños Santos (the Holy Children), María Sabina possessed the keys to the very architecture of the universe.